The Anti-Ribosomal P Protein Antibody IgG test detects autoantibodies against ribosomal P proteins, primarily used as a specific marker for Systemic Lupus Erythematosus (SLE), often pointing to lupus nephritis, psychosis, or severe disease, though also seen in other conditions like Sjögren’s or hepatitis. It helps diagnose SLE, especially when other antibodies (like Anti-dsDNA) are negative, indicating involvement of kidney or neurological systems and aiding in managing this complex autoimmune disorder, requiring blood sample analysis